The Effects of Two Stereoisomers of N-Acetylcysteine on Photochemical Damage by UVA and Blue Light in Rat Retina

1999 ◽  
Vol 70 (3) ◽  
pp. 353 ◽  
Author(s):  
Eelco M. Busch ◽  
Theo G. M. F. Gorgels ◽  
Joan E. Roberts ◽  
Dirk van Norren
Keyword(s):  
Blue Light ◽  
Rat Retina ◽  
Photochemical Damage

The Effects of Two Stereoisomers of /V-Acetylcysteine on Photochemical Damage by UVA and Blue Light in Rat Retina

1999 ◽  
Vol 70 (3) ◽  
pp. 353-358 ◽  
Author(s):  
Eelco M. Busch ◽  
Theo G. M. F. Gorgels ◽  
Joan E. Roberts ◽  
Dirk Norren
Keyword(s):  
Blue Light ◽  
Rat Retina ◽  
Photochemical Damage

Blue light hazard: does rat retina make relevant model for discussing exposure limit values applicable to humans?

2019 ◽  
Vol 54 (2) ◽  
pp. 141-147
Author(s):  
S. Point ◽  
M. Beroud
Keyword(s):  
Blue Light ◽  
Rat Model ◽  
Relevant Model ◽  
Limit Values ◽  
Led Lighting ◽  
Rat Retina ◽  
Model Experiments ◽  
Exposure Limit ◽  
Scientific Papers

Recent scientific papers have drawn attention to potential blue light hazard associated with the use of LED lighting and the validity of exposure limit values of safety norms has been called into question. But can data coming from rat model experiments be extrapolated to human? This article provides some basic recommendations regarding rat retinal irradiance calculations and its potential extrapolation to human.

scholarly journals Mitochondria as Potential Targets and Initiators of the Blue Light Hazard to the Retina

2019 ◽  
Vol 2019 ◽  
pp. 1-20 ◽  
Author(s):  
Jin-Xin Tao ◽  
Wen-Chuan Zhou ◽  
Xin-Gen Zhu
Keyword(s):  
Blue Light ◽  
High Energy ◽  
Future Research ◽  
Damage Potential ◽  
Light Emitting ◽  
Photochemical Damage ◽  
Potential Risks ◽  
Light Components ◽  
And Function ◽  
White Light Emitting Diodes

Commercially available white light-emitting diodes (LEDs) have an intense emission in the range of blue light, which has raised a range of public concerns about their potential risks as retinal hazards. Distinct from other visible light components, blue light is characterized by short wavelength, high energy, and strong penetration that can reach the retina with relatively little loss in damage potential. Mitochondria are abundant in retinal tissues, giving them relatively high access to blue light, and chromophores, which are enriched in the retina, have many mitochondria able to absorb blue light and induce photochemical effects. Therefore, excessive exposure of the retina to blue light tends to cause ROS accumulation and oxidative stress, which affect the structure and function of the retinal mitochondria and trigger mitochondria-involved death signaling pathways. In this review, we highlight the essential roles of mitochondria in blue light-induced photochemical damage and programmed cell death in the retina, indicate directions for future research and preventive targets in terms of the blue light hazard to the retina, and suggest applying LED devices in a rational way to prevent the blue light hazard.

scholarly journals Blue light induced apoptosis in rat retina

Eye ◽  
1999 ◽  
Vol 13 (4) ◽  
pp. 577-583 ◽  
Author(s):  
Jiangmei Wu ◽  
Stefan Seregard ◽  
Berit Spångberg ◽  
Margareta Oskarsson ◽  
Enping Chen
Keyword(s):  
Blue Light ◽  
Rat Retina ◽  
Induced Apoptosis

Distribution of calcium and sulphur in the blue-light-exposed rat retina

1995 ◽  
Vol 233 (3) ◽  
pp. 163-167 ◽  
Author(s):  
Enping Chen ◽  
Jan Pallon ◽  
Bo Forslind
Keyword(s):  
Blue Light ◽  
Rat Retina

scholarly journals Temporal sequence of changes in rat retina after UV-A and blue light exposure

1999 ◽  
Vol 39 (7) ◽  
pp. 1233-1247 ◽  
Author(s):  
Eelco M Busch ◽  
Theo G.M.F Gorgels ◽  
Dirk van Norren
Keyword(s):  
Blue Light ◽  
Light Exposure ◽  
Temporal Sequence ◽  
Rat Retina

Cytochrome oxidase activity in rat retina after exposure to 404 nm blue light*

2009 ◽  
Vol 71 (S208) ◽  
pp. 825f-831f ◽  
Author(s):  
Enping Chen ◽  
Per G. Söderberg ◽  
Bo Lindström
Keyword(s):  
Cytochrome Oxidase ◽  
Blue Light ◽  
Oxidase Activity ◽  
Rat Retina ◽  
Cytochrome Oxidase Activity

scholarly journals Müller Cell Response to Blue Light Injury of the Rat Retina

2008 ◽  
Vol 49 (8) ◽  
pp. 3559 ◽  
Author(s):  
Ianors Iandiev ◽  
Antje Wurm ◽  
Margrit Hollborn ◽  
Peter Wiedemann ◽  
Christian Grimm ◽  
...  
Keyword(s):  
Blue Light ◽  
Cell Response ◽  
Rat Retina
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